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Customer Case Study – Virus Clearance Studies with Sartobind® Q 

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Customer Case Study – Virus Clearance Studies with Sartobind® Q 

A large biopharmaceutical company partnered with Sartorius to test Sartobind® Q membrane adsorbers as an alternative to competitor membranes for virus clearance. The goals were to address supply issues, determine maximum loading capacities for different molecules, and confirm scalability between Pico and Nano devices. The study used MMV-spiked materials to assess performance.

 

Key Takeaways:

  1. Economic and Practical Benefits – Using Pico devices reduced required test material by 12.5× and adsorber costs by 8× during validation studies.
  2. High Capacity and Robust Clearance – Sartobind® Q membranes achieved loadings up to 20 kg/L with consistent LRV of 4–5, enabling cost-effective use at manufacturing scale.
  3. Better than Competitor – Sartobind® Q delivered 1–1.5 higher LRVs compared to competitor membranes, making it a strong alternative for large-scale virus clearance.

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