Boost accuracy and precision in kinetics, affinity, and quantitation assays by maintaining analyte concentrations over time (16 hours) with new evaporation control capabilities.
High-Speed Data for Precise Kinetic Insights
Accurately capture fast kinetics with the enhanced data acquisition feature.
Best-in-Class Sensitivity
Improved signal-to-noise ratio for precise detection of low molecular weight and low-concentration analytes.
Disposable, single-use fiber optic biosensors with optional reuse by regeneration and re-racking in the sensor tray
Information Provided
Yes/No binding - Kinetic and affinity analysis (kobs, ka, kd, KD) - Specific and selective detection of molecules, even in crude samples - Relative and absolute quantitation of specific proteins in crude matrices or purified samples - Relative potency (EC50) and Inhibition (IC50) analysis?
Sample Types
Proteins, antibodies, peptides, DNA, RNA, liposomes, viruses and VLPs in various media including serum, buffers containing DMSO, periplasmic fractions, bacterial cells, nanoparticles, untreated cell culture supernatants and crude cell lysates
Number of Spectrometers
8
Maximum Simultaneous Reads
8
Data Collection Rate
Variable
Sample Position and Format
One standard 96-well or 384-well black, flat bottom microplate, or 384-well black tilted well plate
The Octet® R8e features advanced evaporation control for the 96-well plate format, allowing for up to 16 hours of uninterrupted operation while maintaining analyte integrity, reducing the need for manual intervention, and improving data accuracy. This means the system delivers consistent, reliable results even during long or over-night experiments.
The Octet® R8e System is a cutting-edge, 8-channel biolayer interferometry (BLI) system designed for real-time, label-free biomolecular analysis. It features a fluidic-free design that minimizes maintenance, simplifies workflows, and ensures consistent data accuracy. The Octet® R8e boasts best-in-class sensitivity, extended walk-away operation, and supports GxP compliance. With its high throughput and robust performance, the system is ideal for complex drug discovery and process development applications.
With compatibility for both 96- and 384-well plates, the Octet® R8e is designed to support high-throughput workflows. The system’s 8 channels enable parallel data acquisition, allowing labs to process multiple samples simultaneously, boosting efficiency and maximizing productivity.
Yes, the Octet® R8e is designed for seamless assay transferability across platforms. Methods developed on older Octet® BLI systems can be easily transferred without compromising data integrity or comparability, ensuring smooth transitions and consistent results across your lab’s operations.
The Octet® R8e requires as little as 40 µL of sample per well, making it highly efficient and cost-effective, especially when working with precious or limited sample quantities. This low sample volume capability helps conserve reagents and minimize costs. Furthermore, the measurement is non-destructive and the sample plate can be recovered for further usage.
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